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Cagrilintide
Price range: $80.00 through $430.00
Cagrilintide is a long-acting amylin analogue medication being developed for the treatment of obesity and type 2 diabetes. Amylin is a hormone that helps regulate appetite and blood sugar levels. By mimicking the effects of amylin, cagrilintide is thought to help people lose weight and control their blood sugar.
Cagrilintide is currently being studied in clinical trials, either alone or in combination with another medication called semaglutide. Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist, which is another type of medication that is effective for weight loss and blood sugar control.
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Description
Benefits of Cagrilintide
Cagrilintide has a different mechanism of action from GLP-1 receptor agonists (such as semaglutide), but the two can synergistically enhance weight loss.
✅ Delay gastric emptying → Increase satiety and reduce food intake
✅ Inhibit hypothalamic appetite signals → Reduce hunger
✅ Regulate metabolism → May improve blood sugar and fat metabolism
Clinical effect (Phase II trial data)
1. Monotherapy (obesity)
After 26 weeks of treatment, the average weight loss of patients was:
Low-dose group: ~6%
High-dose group: ~10.8% (significantly better than placebo)
2. Combined with semaglutide (CagriSema regimen)
Cagrilintide + semaglutide showed stronger weight loss effects in early trials:
Average weight loss at 32 weeks: ~15-17% (better than semaglutide or Cagrilintide alone)
Some patients lost more than 20%
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