SLU-PP–332

Key Properties

✦Chemical Name: (E)-4-Hydroxy-N’-(naphthalen-2-ylmethylene)benzohydrazide
✦Molecular Formula: C₁₈H₁₄N₂O₂
✦Molecular Weight: 290.32 g/mol
✦Appearance: White to off-white solid
✦Purity: ≥ 98% (HPLC)
✦Solubility: Soluble in DMSO (up to 100 mg/mL with sonication)
✦Storage: Store powder at –20°C; DMSO solutions can be stored at –80°C for up to 6 months or –20°C for 1 month.

SLU-PP-332 mechanism of action

✦SLU-PP-332 works by activating estrogen-related receptors (ERR), including ERR-alpha, ERR-beta, and ERR-Gamma in the body. As an agonist, SLU-PP-332 doesn’t mimic ERRs’ function directly. It binds and stimulates them to enhance their natural function in mitochondrial Biogenesis, energy production, and fat metabolism.
✦Energy Production: SLU-PP-332 boosts the function of mitochondria by activating ERRs, allowing cells to produce more energy.
✦Fat Burning: Better mitochondrial function can enhance fatty acid oxidation, making SLU-PP-332 help break down fat and convert it into usable energy.
✦Muscle Health: In muscles, more energy makes SLU-PP-332 support endurance and reduce fatigue.

Benefits of SLU-PP-332

✅Fat loss: By enhancing lipolysis, SLU-PP-332 can utilize stored fat for energy, and it can also increase the oxidation of fatty acids for energy as well. This makes it appealing for individuals aiming for fat loss and improved metabolic health.
✅Weight loss: SLU-PP-332 was developed as an exercise mimetic; it doesn’t control appetite to let you eat less, nor does it need you to exercise more to lose weight. It just mimics exercise to let the muscles become lean and lose fat.
✅Increased Endurance: The clinical studies have shown that mice treated with SLU-PP-332 can run longer and farther. We can expect increased Endurance when we use SLU-PP-332.
✅Better Resting Metabolic rate: SLU-PP-332 can make the body burn calories even without exercise.
✅Heart Health: Preliminary data suggests SLU-PP-332 can strengthen the heart muscle in mice to treat heart failure.
✅Muscle mass and Muscle recovery: By activating specific pathways, SLU-PP-332 can enhance mitochondrial function in muscle tissues, which can lead to better endurance and recovery, especially beneficial for muscle recovery due to aging.