Semaglutide: Metabolic & Weight Support

$40.00

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist that plays a crucial role in managing blood sugar levels, weight regulation, and cardiovascular health. Originally developed as a treatment for type 2 diabetes, semaglutide has gained significant attention for its additional benefits, including weight loss and potential neuroprotective effects.

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Description

Benefits of Semaglutide

Semaglutide works by activating GLP-1 receptors:
✅ Promote insulin secretion (blood sugar dependence, reduce the risk of hypoglycemia)
✅ Inhibit glucagon secretion (reduce liver glucose output)
✅ Delay gastric emptying (increase satiety, reduce food intake)
✅ Regulate the hypothalamic appetite center (reduce hunger)

Clinical effects

1. Hypoglycemic effect (type 2 diabetes)
It can reduce HbA1c (glycosylated hemoglobin) by 1.5%~2.1% (SUSTAIN trial).
Cardiovascular benefits: In high-risk type 2 diabetes patients, the risk of major adverse cardiovascular events (MACE) was significantly reduced by 26% (SUSTAIN-6 trial).

2. Weight loss effect (obesity)
In the STEP clinical trial, the average weight loss of obese/overweight patients (without diabetes) was:
(2.4mg/week): 15%~18% (about 15-20kg)
Some patients lost more than 20% (close to the effect of bariatric surgery).

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