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This product is intended solely for use as a research chemical in vitro and laboratory experimentation by licensed, qualified professionals.
Tesofensine is an investigational weight-loss medication originally developed for Alzheimer’s and Parkinson’s disease but repurposed due to its potent appetite-suppressing and metabolic effects.
| Specifications | Price |
|---|---|
| 500mcg (0.5mg) × 100 tablets/bottle | $45.00 |
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| Characteristic | Details |
|---|---|
| Molecular Formula | C17H23Cl2NO |
| Molecular Weight | 328.28 |
| CAS Number | 195875-84-4 |
Tesofensine belongs to the class of triple monoamine reuptake inhibitors (TRIs). It works by blocking the reuptake of three key neurotransmitters in the brain:
Serotonin (5-HT): Regulates mood and satiety.
Noradrenaline (NA): Influences energy expenditure and alertness.
Dopamine (DA): Impacts reward and motivation.
By increasing the levels of these neurotransmitters, Tesofensine helps suppress appetite, reduce food cravings, and boost metabolism, leading to reduced calorie intake and enhanced fat loss.
Significant Weight Loss: In clinical trials, patients lost 11.3–12.8 kg (25–28 lbs) in 24 weeks—double the weight loss of placebo groups. 10% average body weight reduction at moderate doses (0.5 mg/day).
Metabolic Improvements: Reduces visceral fat, insulin resistance, and LDL cholesterol. Enhances fatty acid oxidation (nighttime energy expenditure).
Non-Surgical Alternative: Comparable to bariatric surgery (20% weight loss) but without invasive procedures.
Like many compounds that act on neurotransmitters, Tesofensine may cause side effects. The most commonly reported include:
Dry mouth
Insomnia or difficulty sleeping
Increased heart rate or blood pressure
Mild gastrointestinal issues (nausea, constipation)
Close monitoring is advised during use, especially in individuals with cardiovascular concerns.
Tesofensine is still considered an e*perimental compound and is not yet approved for general medical use. Research continues to evaluate its safety, effectiveness, and long-term benefits as a weight management solution.
All products are sold solely for scientific research purposes. Researchers are responsible for ensuring compliance with local regulations and institutional guidelines. Keep out of reach of children and unauthorized personnel.
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