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Dopamine D2 Receptor Agonist

This product is intended solely for use as a research chemical in vitro and laboratory experimentation by licensed, qualified professionals.

Cabergoline : Dopamine D2 Receptor Agonist

Cabergoline is a type of ergot derivative and a long-acting dopamine receptor agonist. It can inhibit the synthesis and secretion of PRL at the hypothalamic and pituitary levels, reduce the PRL level in the serum, and effectively and persistently suppress the secretion of prolactin. It has a significant dopamine receptor agonistic effect and is widely used in the treatment of various diseases.ous diseases.

Specifications Price
0.25mg × 100 tablets $85.00
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Characteristic Details
Molecular Formula C26H37N5O2
Molecular Weight 451.60
CAS Number 81409-90-7

Cabergoline stimulates dopamine receptors in the brain, which in turn suppresses the secretion of prolactin from the pituitary gland. This mechanism helps restore hormonal balance and reduce symptoms associated with high prolactin.

Hyperprolactinemia: The main application of cabergoline is to treat hyperprolactinemia caused by idiopathic or pituitary adenoma. By acting on dopamine receptors, it reduces e*cessive prolactin secretion, effectively improving related symptoms such as irregular menstruation and infertility problems.
Clinical application in Parkinson’s disease: Cabergoline is also used in the treatment of Parkinson’s disease. It can be used alone or in combination with levodopa to alleviate patients’ symptom fluctuations, reduce the dosage requirement of levodopa, and improve the quality of patients’ daily life.
Potential in breast cancer treatment: Cabergoline also shows certain potential in breast cancer treatment. Although the evidence is not yet sufficient, its agonist effect on dopamine receptors may be effective for some patients.
Other therapeutic fields: Besides the above uses, cabergoline is also applied in the veterinary field, such as regulating the reproductive cycle of dogs and being used as an abortion drug. In human medicine, it is also attempted to be used to inhibit lactation, but it is not recommended as a routine treatment.

Like most medications, cabergoline may cause side effects, especially when taken in higher doses. Commonly reported effects include:

  • Nausea and dizziness

  • Fatigue or drowsiness

  • Low blood pressure

  • Headache

In rare cases, long-term use at high doses may be linked to heart valve issues, so regular medical supervision is essential.

All products are sold solely for scientific research purposes. Researchers are responsible for ensuring compliance with local regulations and institutional guidelines. Keep out of reach of children and unauthorized personnel.

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