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This product is intended solely for use as a research chemical in vitro and laboratory experimentation by licensed, qualified professionals.
Orforglipron is a once-daily oral small-molecule (non-peptide) GLP-1 receptor agonist that e*erts effective antidiabetic effects by enhancing glucose-dependent insulin secretion and improving energy balance. The drug can be taken at any time of day and imposes no specific dietary or fluid intake restrictions. Originally discovered by Chugai Pharmaceutical Co., Ltd., Orforglipron was licensed to Eli Lilly and Company for development in 2018. Lilly is currently advancing Orforglipron through the new drug approval process.
| Specifications | Price |
|---|---|
| 12mg × 30 tablets | $59.00 |
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| Property | Details |
|---|---|
| Molecular Formula | C₄₈H₄₈F₂N₁₀O₅ |
| Molecular Weight | 882.96 g/mol |
| CAS Number | 2212020-52-3 |
Mimics GLP-1: The drug activates GLP-1 receptors, which helps regulate insulin and glucagon production.
Slows Gastric Emptying: This keeps food in the stomach longer, helping control hunger and prevent rapid sugar absorption.
Reduces Appetite: Patients often e*perience decreased cravings and smaller portion sizes.
Blood Glucose Control: In Phase 3 clinical studies of Orforglipron, the mean reduction in glycated hemoglobin (HbA1c) across all dose groups ranged from 1.3% to 1.6%.
Weight Loss: At the highest dose, once-daily Orforglipron achieved a mean weight loss of 7.3 kg (7.9%).
Safety: Overall safety and tolerability of Orforglipron in the ACHIEVE-1 study were consistent with injectable GLP-1 drugs.
Convenience: As a non-peptide small-molecule GLP-1 agonist, it offers superior oral bioavailability and simplified dosing regimen.
All product is sold solely for scientific research purposes. Researchers are responsible for ensuring compliance with local regulations and institutional guidelines. Keep out of reach of children and unauthorized personnel.
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